Description
ChemicalBook > CAS DataBase List > 5'-DEOXYADENOSINE

5'-DEOXYADENOSINE

Description
Product Name
5'-DEOXYADENOSINE
CAS No.
4754-39-6
Chemical Name
5'-DEOXYADENOSINE
Synonyms
5′-dAdo;5'-DEOXYADENOSINE;5’-deoxy-adenosin;5'-DEOXYADENOSINE;Adenosine, 5'-deoxy-;2'-Deoxycytidine Monohydrate(2'-dC ? H?O);9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine;6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine;(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol;(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol
CBNumber
CB5163003
Molecular Formula
C10H13N5O3
Formula Weight
251.24
MOL File
4754-39-6.mol
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5'-DEOXYADENOSINE Property

Melting point:
210-212 °C
Boiling point:
595.0±60.0 °C(Predicted)
Density 
1.93±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 15 mg/ml
form 
A crystalline solid
pka
13.29±0.70(Predicted)
InChIKey
XGYIMTFOTBMPFP-KQYNXXCUSA-N
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Safety

WGK Germany 
3
RTECS 
AU7358650
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D1771
Product name
5′-Deoxyadenosine
Purity
methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate
Packaging
25mg
Price
$264
Updated
2024/03/01
Cayman Chemical
Product number
29619
Product name
5''-Deoxyadenosine
Packaging
10mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
29619
Product name
5''-Deoxyadenosine
Packaging
250mg
Price
$541
Updated
2024/03/01
Cayman Chemical
Product number
29619
Product name
5''-Deoxyadenosine
Packaging
50mg
Price
$158
Updated
2024/03/01
Cayman Chemical
Product number
29619
Product name
5''-Deoxyadenosine
Packaging
100mg
Price
$296
Updated
2024/03/01
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5'-DEOXYADENOSINE Chemical Properties,Usage,Production

Description

5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material, which has long been of interest in understanding the mechanism of aging, neurodegenerative diseases, and carcinogenesis. 

Uses

5′-Deoxyadenosine has been used:

  • as a standard in mass spectroscopy
  • as an inhibitor for screening thymidine phosphorylase activity
  • as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay

Definition

ChEBI: A 5'-deoxyribonucleoside compound having adenosine as the nucleobase.

Biochem/physiol Actions

5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes.

5'-DEOXYADENOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-DEOXYADENOSINE Suppliers

Canada 1 China 45 Germany 1 Switzerland 1 United Kingdom 2 United States 7 USA 1 Global 58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58

4754-39-6, 5'-DEOXYADENOSINERelated Search:

N6,N6-DIMETHYLADENOSINE ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE 2',3'-O-Isopropylideneadenosine 5'-Tosyladenosine 5'-(Methylthio)-5'-deoxyadenosine N6-BENZYLADENOSINE 2-Chloroadenosine Cyclic AMP Vidarabine Adenosine 5'-monophosphate monohydrate Bucladesine sodium 3'-ADENYLIC ACID 8-BROMOADENOSINE ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT 5'-IODO-5'-DEOXYADENOSINE N6-BENZOYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE DMT-dA(bz) Phosphoramidite N6-BZ-2'-DEOXYADENOSINE

  • 5’-deoxy-adenosin
  • (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-methyl-oxolane-3,4-diol
  • 6-Amino-9-(5-deoxy-β-D-ribofuranosyl)-9H-purine
  • 9-(5-Deoxy-β-D-ribofuranosyl)-9H-purine-6-amine
  • 5'-DEOXYADENOSINE
  • Adenosine, 5'-deoxy-
  • 5′-dAdo
  • 2'-Deoxycytidine Monohydrate(2'-dC ? H?O)
  • 5'-Deoxyadenosine methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate
  • (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol
  • inhibit,5'DEOXYADENOSINE,5'-Deoxyadenosine,Endogenous Metabolite,Inhibitor,Orthopoxvirus,5' DEOXYADENOSINE
  • 5'-DEOXYADENOSINE
  • 4754-39-6
  • BioChemical
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides